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Neither Chelsea Handler nor Piers Morgan are known to hold back, so when the former interviewed the latter Wednesday, the wisecracks flew a mile a minute.

As soon as Morgan, 47, sat down on Chelsea Lately, she asked, "What are you looking at?"

His reply, "Well, you either had plastic surgery or a makeover, ’cause you look really hot today."

That "compliment" drew a typical response from Handler, 37: "Oh, you’re so annoying."

"You’re so obnoxious. You wonder why everybody hates you! I specifically covered up so you couldn’t look at me and undress me with your molester eyes!"

 

Morgan then made a crack about Hander’s drinking before they got down to business. It’s his two-year anniversary at CNN, which Piers says means one thing.

Handler interjected: "Let me guess – you’re a better interviewer than I am. I’m not pretending to be a great interviewer. I’m not even pretending to be good at my job!"

Morgan: "Both things are clearly apparent today. But I can help you."

Handler: "You can suck my a$$" she said. "I mean, really."

And that was just the first three minutes, people!